Gracey, check if your flight will be fitted with the new business class. If so, then the two middle seats are much more accessible than the old herringbone business seats. Then again, you'd still need to have your LO sitting on your lap with the lap belt during take off and landing. If you're flying red-eye then the business class lay-flat seats would make more sense. Your little one will have their own space to sleep. But if you're flying during the day, the 3 economy seats would be more sensible. Also, when choosing the 3 economy seats, I prefer not to have the bassinet row because the middle armrests are fixed and cannot be raised. Anyway, those bassinets are tiny and by the time they're 6 months even, those things are way too small.